PLATELET-RICH PLASMA
Platelet Rich Plasma (PRP) is blood plasma that has been enriched with platelets. As a concentrated source of autologous platelets, PRP contains several different growth factors and other cytokines that stimulate the healing of bone and soft tissue.
Blood-Derived Growth Factors
Growth Factor Production Known Effects
Epidermal Growth Factor (EGF)
Plays a significant role in the regulation of cell growth, proliferation, and the differentiation during the remodeling phase. Stimulates keratinocyte and fibroblast production.
Transforming Growth Factor (TGF)
Promotes angiogenesis which is the physiological process involving the growth of new blood vessels.
Vascular Endothelial Growth Factor (VEGF)
An important signaling protein involved in both vasculogenesis and angiogenesis, the growth of the blood vessels from pre-existing vasculature.
Fibroblast Growth Factor (FGF)
Promotes angiogenesis, granulation, and epithelialization for the intricate process of the skin repairing itself after injury.
Platelet-Derived Growth Factor (PDGF)
Attracts macrophages and fibroblasts to the zone of injury. Promotes collagen growth and proteoglycan synthesis.
Interleukins, Macrophages, keratinocytes, endothelial cells, Iymphocytes, fibroblasts, osteoblasts, basophils, mast cells.
Activates fibroblasts differentiation. Induces collagen and proteoglycan synthesis for healthy cell production and repair of damaged tissues.
Collagen Stimulating Growth Factor.
Stimulates granulocyte and macrophage proliferation for the growth of healthy tissue and blood cells.
Keratinocyte Growth Factor (KGF)
Keratinocyte migration, differentiation, and proliferations directly enhance wound healing and the generation of new skin.